SINGLE-USE : bags and assemblies

JYSS BIO Single-Use Bags and Assemblies

A Complete Range for Your Bioprocesses

Blanc-Labo's single-use solutions cover the main fluid handling operations:

• aseptic storage of culture media;

• preparation and storage of buffers;

• transfer of intermediate products;

• feeding and harvesting of bioreactors;

• liquid-liquid or solid-liquid mixing;

• sampling;

• dispensing of a fluid to multiple containers;

• packaging and transport of biological fluids;

• cell culture in bags;

• viral inactivation and intermediate process operations.

2D and 3D Storage Bags

Single-use storage bags are designed for the packaging, storage, and transfer of fluids used in pharmaceutical and biotechnological processes.

They can hold, in particular:

• culture media;

• buffer solutions;

• intermediate products;

• biological samples;

• Harvesting solutions;

• Feeding solutions;

• Cell culture fluids.

2D formats are suitable for small to medium volumes and routine laboratory procedures.

3D formats are designed for larger volumes and can be installed in a tray, container, or support cart.

Single-use mixing bags

JYSS BIO mixing bags are available in closed versions with magnetic stirring or in open versions.

They are particularly well-suited for preparing:

• Culture media;

• Buffer solutions;

• Process solutions;

• Liquid-liquid mixtures;

• Powder-liquid mixtures;

• Solutions containing hydrated or hydrophobic particles.

The bags can be configured with a square or cylindrical shape depending on the mixing system used.

Certain configurations can also be designed for integration with existing mixing platforms in your laboratory or production unit.

Cell Culture Bags and Bioreactors

JYSS BIO develops bags for single-use cell culture systems.

Depending on the bioreactor configuration, the bags can integrate the necessary process components:

• feed lines;

• gas lines;

• harvesting lines;

• vent filters;

• sampling ports;

• tubing;

• fittings;

• compatible sensors and measurement interfaces;

• a stirring system adapted to the equipment.

These solutions are particularly suited to work with animal cells, recombinant proteins, antibodies, vaccines, cell therapies, and other bioprocesses requiring a closed environment.

Custom Single-Use Assemblies

A single bag is not always sufficient. The system's performance depends on the entire circuit in contact with the product.

JYSS BIO can create assemblies incorporating:

• one or more bags;

• platinum-vulcanized silicone tubing;

• Thermoplastic TPE tubing;

• PVC tubing depending on the application;

• Quick-connect fittings;

• Y, T, or cross fittings;

• Diameter reducers;

• Tri-Clamp sanitary fittings;

• Luer fittings;

• Sampling ports;

• Ventilation filters;

• Sterile connectors;

• Clamps and disconnect devices.

• Each assembly can be defined based on your drawing, bill of materials, or in consultation with our technical team.

Multi-pocket assemblies for sampling and dispensing

Multi-pocket assemblies facilitate repeated sampling or dispensing operations.

They allow, for example:

• several successive samplings without opening the process;

• distribution of a batch between several pockets;

• preparation of control samples;

• supplying multiple pieces of equipment;

• to reduce the number of connections made by the operator.

• The bag volumes, tubing lengths, number of branches, and fitting types can be adapted to your installation.

JYSS BIO bags are manufactured, according to your choice, from either Renolit 9101 film or the 9-layer EB1596 film developed by JYSS for biopharmaceutical applications.

The choice of film and configuration must be confirmed based on the nature of the fluid, the contact time, the temperature, transport constraints, and the required level of documentation.

While European customers most often choose Renolit, which they are familiar with, both films are equivalent and allow JYSS to continue deliveries even in the event of supply constraints for Renolit.

All E&L (Extractables and Leachables) tests are performed by the Swiss General Surveillance Company (SGS).

Why order your JYSS BIO solutions from Blanc-Labo?

Blanc-Labo provides the technical and commercial interface between your team and the manufacturer.

We help you:

• formalize your needs;

• Verify the assembly's consistency;

• Select the components;

• Manage technical discussions with the manufacturer;

• Obtain available qualification documents;

• Organize your recurring orders;

• Adapt the configuration as your process changes.

Our teams work in France and Switzerland with research laboratories, biotechnology companies, pharmaceutical sites, and pilot plants.

Are you looking for a standard bag or a fully customized assembly?

Send us your drawing, bill of materials, or a photograph of your existing setup.

Request a technical datasheet, a sample, or a customized quote.

Information needed to prepare a quote:

Intended use: storage, transfer, mixing, culture, or sampling;

• Type of fluid;

• Nominal and working volumes;

• Minimum and maximum temperatures;

• Storage or contact time;

• Expected flow rates and pressures;

• Tube diameters;

• Required fittings;

• Number of inlets and outlets;

• Desired filters or sampling ports;

• Required sterilization method;

• Required tests and certifications;

• Estimated annual quantity.

• A drawing, even a simple hand-drawn one, often allows us to move forward quickly.

Less preparation before use

The circuit is supplied pre-assembled according to a predefined configuration. This reduces manual assembly and repeated connections for the operator.

No cleaning of the product circuit

After use, the single-use components are removed. This eliminates the need to clean and sterilize a tank or fixed line for the operation in question.

Reduced risk of cross-contamination

The product comes into contact with a new circuit for each batch. This approach is particularly advantageous in multi-product units or during frequent campaign changes.

Rapid implementation

Single-use technologies shorten preparation phases between batches and increase equipment availability.

Configuration tailored to the process

Diameters, lengths, fittings, filters, and sampling points can be defined according to your installation rather than adapting your process to a standard assembly.

Blanc-Labo provides the technical and commercial interface between your team and the manufacturer.

We help you to:

• formalize your requirements;

• verify the assembly's consistency;

• select the components;

• manage technical communication with the manufacturer;

• obtain the available qualification documents;

• organize your recurring orders;

• adapt the configuration as your process changes.

Our teams work in France and Switzerland with research laboratories, biotechnology companies, pharmaceutical sites, and pilot plants.